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By Dennis T. Mangano M.D., Ph.D (auth.), Theodore H. Stanley MD, W. Clayton Petty MD (eds.)

ISBN-10: 0898385598

ISBN-13: 9780898385595

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The stress response - metabolic changes During stress, substrates are mobilised from storage sites and other tissues and redistributed to central organs. These metabol ic changes are mediated by the stress hormones especially the catecholamines, cortisol and glucagon. l Glucose production is increased due mainly to hepatic glycogenolysis and gluconeogenesis. In addition, the uptake of glucose in the peripheral tissues is impaired. 2 The resultant hyperglycaemia is proportional to the severity of the stress reaction.

Am J Cardiol 32:592-606, 1973. 9. Hollander W: Hypertension, antihypertensive drugs and atherosclerosis. Circulation 48:1112-1127, 1973. 10. Kannel WB, Schwartz MJ, McNamara PM: Blood pressure and risk of coronary heart disease - The Framingham study. Dis Chest 56:43, 1969. 11. Inter-Society Commission for Heart Disease Resources. Arteriosclerosis Study Group and Epidemiology Study Group: Primary prevention of the atherosclerotic diseases. Circulation 44:A263, 1971. 12. Prys-Roberts C: Medical problems of surgical patients: Hypertension and ischaemic heart disease.

Paton WD, Zaimis EJ: The methonium. Pharmacol Rev 4:219-253, 1952. 41. Boura AL, Green AF: The actions of bretylium: adrenergic neurone blocking and other effects. Br J Pharmacol 14:536-548, 1959. G. D. The purpose of this report is to update a previous, more detailed review of calcium entry blockers and the implications these drugs have on anesthesia practice.! 3- 11 Calcium Antagonists There are three structurally diverse calcium antagonists available at present (1983) in the United States: nifedipine (Procardia), verapamil (Isoptin, Calcan) and diltiazem (Cadiozem).

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Anesthesia and the Cardiovascular System: Annual Utah postgraduate course in anesthesiology 1984 by Dennis T. Mangano M.D., Ph.D (auth.), Theodore H. Stanley MD, W. Clayton Petty MD (eds.)


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